I think some countries require that the terms of employment be somewhat related to the nature of the work. Contraceptives might be banned by that. (IANAL, just someone who's had this explained by a lawyer.)
In a fully remote company, where you never meet customers, vendors or other employees, requiring vaccination might be viewed by a court as unrelated to the work. If you're supposed to meet customers or other employees and there's a pandemic going on, though...
There was a case her in Denmark (which, normally, have much stronger employment laws than the US) where it turned out that a company could require its workers to exercise (and they were computer programmers, so it wasn't directly related to their job) provided that it happened in working hours.
The military and sports teams certainly mandate exercise (explicitly in the military's case and at least implicitly but very likely explicitly for sports teams).
Military pilots are also issued "go pills" (dextroamphetamine) for long combat and long single-pilot transit sorties.
What about “pep-pills”? Can they require that?
Can they coerce anti-psychotic drugs to those who need this medication to stay balanced?