Yes, it does, which is why the iPhone 4 was a terrible design. Pull the phone out of your pocket, and there's a 3-in-4 chance that you're "holding it wrong" right off the bat because the front and back feel the same.
No, thanks. Every surface on a phone needs to feel at least subtly different.
The glass front and the metal back always felt different to me... and in any case, the very first thing I did is look for the home button with my thumb.