Without distracting from you central point (which I very much agree with), please read the science around hydroxychloroquine, not the news. It works best taken with Zinc, and early when symptoms first present.
There are zero studies that disprove zinc + early has a strong effect. You are wrong. Also, the lancet study was retracted for flawed methodology, other studies show slight benefit of hydroxychloroquine. There are zero studies that show it has no effect.
You can’t show that it has zero effect without indefinite numbers of patients enrolled in the study. It hasn’t shown any dramatic improvements in the studies that are there. The rest is a tradeoff between enrolling even more patients into studies to prove small improvements (or not) or to move on and spend resources on finding things that do have a major impact.
There's no studies yet. But there aren't any preliminary results that look promising, and the only people who think it is promising also thought hydroxychloroquine was.
So it's pretty unlikely it's going to do anything.
> In univariate analyses, zinc sulfate increased the frequency of patients being discharged home, and decreased the need for ventilation, admission to the ICU, and mortality or transfer to hospice for patients who were never admitted to the ICU. After adjusting for the time at which zinc sulfate was added to our protocol, an increased frequency of being discharged home (OR 1.53, 95% CI 1.12-2.09) reduction in mortality or transfer to hospice remained significant (OR 0.449, 95% CI 0.271-0.744). Conclusion: This study provides the first in vivo evidence that zinc sulfate in combination with hydroxychloroquine may play a role in therapeutic management for COVID-19.
"This study provides the first in vivo evidence that zinc sulfate in combination with hydroxychloroquine may play a role in therapeutic management for COVID-19."
"we hypothesize that CQ/HCQ plus zinc supplementation may be more effective in reducing COVID-19 morbidity and mortality than CQ or HCQ in monotherapy."
"We seek to draw the attention of the scientific community to the possibility of drastically reducing the effects of the vi-rus on the affected patients and improving clinical tri-als outcome through the synergistic action of zinc and chloroquine"
"Thirdly, hydroxychloroquine acts as an ionophoric agent for Zinc ions and thus increases the influx of Zinc ions into the cytoplasm of host target cells regardless whether the host target cells are infected or not [10]. Zinc ions adhere to the RNA dependent RNA polymerase enzyme of the virus and stops COVID-19 polymerization intracellularly."
We do need follow up and repeated clinical trials.
