If the time zone difference is San Francisco to London, sure. But I've lived in Pacific while working for a company in Central, and live in Eastern while working for a company in Pacific, and it's not a big deal. You just adjust your daily cycle by a couple of hours.
Domestically, it only gets complicated when you have an entire office of people in a different zone. Then large meetings get hard to schedule around lunch and COB.
Domestically, it only gets complicated when you have an entire office of people in a different zone. Then large meetings get hard to schedule around lunch and COB.