The one quibble is that computationalism – the idea that experience is simply what some kinds of computation feel like from the inside, regardless of the substrate – may or may not be correct. It could be that qualia can only arise in systems that are physically intertwined in particular configurations (see Tononi's IIT), and it could even be that quantum effects are required (I'm skeptical, but who knows). The jury is still out on those question.

Therefore, it may be true that using biological neurons, arranged in a certain configuration, would give rise to qualia like pain in a way that shifting electrons between CPU registers never could. We just don't know.

For more reading, here's a relevant whitepaper by the Qualia Research Institute: https://opentheory.net/PrincipiaQualia.pdf