I have 3 layers: Privacy Badger (with some custom made work), NoScript, AdBlockPlus. I have 'maxed out' all Firefox privacy settings (battery monitoring, geolocation, 3rd party cookies, etc.). I also got some strong hosts file (https://someonewhocares.org/hosts/)
I feel pretty private :)
Also when I go to a website that it doesn't ring a bell, I spend a few seconds 'working on it' (PrivacyBadger, NoScript, ABP) so I won't have to bother again with their crap.
You may want to consider switching from ABP to uBlock Origin. There's lots of articles explaining it in detail, but essentially uBO is open source and ABP is a $50mm/yr business that allows some ads through and I think (but am not positive) have a history of data sharing.
I recommend switching from AdBlock Plus to uBlock Origin.
uBlock Origin is run by what seems to be a very principled and knowledgeable person.
(The only downside I recall from moving from ABP to UBO is if you're a blocklist developer: adding site-specific rules in a form suitable for shared blocklists is currently easier in ABP than UBO. For my current experimental data set, I have manually added over 10,000 such site-specific blocklist rules, mostly one or a few at a time, using the text editor in UBO, but I still prefer UBO to ABP overall.)