Yeah, last holiday I took I felt horrid the entire time. I actually had some fairly bad headaches and ended up getting tests done; they came back normal.
Headaches and fatigue typically happen after the stress, so if you do have a stressful job then it can take a few days or longer to recover.
Even if you like your job and you think it's great, that doesn't mean it isn't stressful. IMHO if you have meetings then your job isn't great, but maybe you're a strange person who enjoys meetings :)
Anyway, all I'm saying is to think carefully about your job and decide whether or not it is right for you.
Also worth getting a sleep study done, in case it is sleep apnea.
And of course, we are watching for cancer. It’s very unlikely at my age, but I definitely can’t rule it out.