As mentioned in the comments on the link, it doesn't work. It just lowers the amount of "clicks". I noticed the bug the same day the Mac mini 2018 came out and have found no solution.
Certain applications - Sibelius seems particularly bad - cause audio glitches that can be cured by restarting coreaudiod.
The other glitching problem I've had is in Ableton Live, where every thirty seconds or so the sound from the audio inputs glitches and breaks up, which makes Live useless for any kind of recording.
This is a known Live bug that has been around for a long time. It seems to be caused by the built-in audio devices competing with external hardware.
Certainly Apple are a long, long way from "It just works" now.
