I would love to have more details about your setup !

Is it on Windows ? Linux ? OSX86 ? When you say plug & play, that means you're not required to reboot or do anything special at all ?

So you have to change all your BIOS settings for PCIE ports to enable hotplug, then you just plug in the EXP-GDC Beast into the ExpressCard slot. Works on both MacOS 10.12 and Windows 10.

It's a Lenovo X220 ThinkPad with the BIOS modification described here: http://x220.mcdonnelltech.com/ The BIOS mod allows me to run 16GB RAM at 1866 MHz. Also has a 500GB SSD running where the 3G card used to be, and swapped out the stock hard drive for another 500GB SSD.