Not really. Rectal administration of drugs is one of the fastest ways to administer a drug outside of IV.

Unfortunately, I found out about it because of a now-deceased friend who succumbed to alcoholism. Near the end, he would drink rectally, since his esophagus was effectively destroyed. Also, since there's no gag reflex to keep you safe, this way is one of the easiest ways to kill yourself with alcohol.

I love learning new things... but not always.