Tobacco, the triangle trade, opium, weed, etc. Several of the states actually had laws on the books that made it a criminal offense to not grow marijuana.
Yes, but hemp was used in industry to make rope, not smoked. Easy to make sensationalist remarks; a little responsible research takes time and trouble.
Regardless of whether or not it was smoked, industrial hemp is still considered a drug today. IIRC you're actually eligible for the death penalty if you grow enough of it.