I don't know about that. From a pure physical health perspective (i.e. discounting convenience, cost and supposed mental health benefits), there are a bunch of exercises that are strictly superior to running. They provide all of the cardio benefits of running, but without the prevalence of joint injury when you crank up the time investment. Some good examples are swimming, biking, or using a rowing machine.
I'm a big believer in the idea that motivation trumps all other considerations when it comes to exercise though, so you should run if you like running.
biking is one of the worst exercises out there. sure you save joints, but your back, neck and possibly erection will suffer instead. Got couple of colleagues/friends who have health issues exactly because of biking.
and if you do road biking, depending on location, you are at mercy of car drivers on narrow roads. even if 99,9% are good and paying attention all the time, sooner or later someone won't. if you do other types of biking, there are other safety issues.
by all means do it if that's your thing, but don't call it super healthy, or safe. take 2 steps back - most of us sit on our a__es all days, so you go and do sport where you... sit on your a__. right.
I think that's a false equivalency - sitting on the bike is not the same kind of sitting as in your office, unless you get a lot more cardio in at your desk than most of us. If you're worried about your erection (or labia), saddles with cutouts are easily available (I like Terry ones myself). And clearly cars are dangerous to runners too, who often rock reflective garments, LED blinkies, etc. much like cyclists.
I'm a big believer in the idea that motivation trumps all other considerations when it comes to exercise though, so you should run if you like running.