I got pretty good with InDesign during high school, where I took Graphic Communications at our vo-tech. It really is an awesome tool for getting print ready. We used it in conjunction with an actual printing press.
If I had to do it now I would use LaTeX though. For me, open always trumps proprietary when available, and because of their proprietary sort of walled garden nature, Adobe is not a company I would like to support.
Open source is cool and all. But I'm not exaggerating when I say that doing the same thing in LaTeX would take years longer than doing it in InDesign, assuming the output of both is close enough to what I'm trying to achieve. So those years count toward something for me.
If I had to do it now I would use LaTeX though. For me, open always trumps proprietary when available, and because of their proprietary sort of walled garden nature, Adobe is not a company I would like to support.