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I don't understand how people can defend his detractors in this particular case. Are you telling me that an image upsampling model that does not contain hard coded bias, and trained on unbiased data will produced biased result? Especially the kind of biased result represented by the error made by the original tweeter who fucked up?


Just curious, but what "error" did the original tweeter make? Did anyone really expect the model to accurately reconstruct the original photo starting from a pixelated mess? That makes no sense to anyone with even a passing knowledge of ML. You're always going to get craploads of bias and variance (i.e. blatant inaccuracy, over and above the bias) in such a setting, even starting from "ideal, unbiased" data. The problem domain is at issue here.


Yeah I get your point. But I guess for this model you can kinda have a concept of the "ideal" training set, where all high frequency features appear at the same rate as in real world.


What's the chance of hitting all 4 of them though? This is a good step in verification but you are awfully too quick to reject their claim.


Read the paper, they actually only match 2 inserts, the other two inserts are modified by the authors in such a way that they are made to match (Table 1).

Both inserts 1 and 2 also match to Streptococcus phage, but a bacteriophage would of course not be such a bold claim as HIV matches are.

Also, be aware that because of the scientific interest in HIV, there are hundreds of HIV strains sequenced, a virus known for its mutation rate (especially in these two proteins gp120 and gag, as they are under pressure to mutate in order to evade the immunesystem). So in such a large library of protein sequences one is bound to find a match of a short 6 letter (amino acid) sequence. That's why E values exist to make a statement about the statistical significance.


For posteriority, here's the link to the Blast results for the second insert: https://blast.ncbi.nlm.nih.gov/Blast.cgi?CMD=Get&RID=39ACRKV...


Hello posteriority here! I wanted to reference these comments in a discussion but the links expired :/


Large HIV database inflating matches is indeed a big concern. But dismissing one miss matches sounds arbitrary: these segments were not arbitrarily selected, but real insertions on tops of sars.


Again, take any random six letter amino acid sequence and chances are high that it matches to some HIV protein.

I just did the experiment with my first name that is coincidentally 6 letters long, and lo and behold: a match to HIV env protein!

Has my first name now been designed by a bioweapons facility?


> Has my first name now been designed by a bioweapons facility?

No, of course not. Your parents were designed by a bioweapons facility, so that they would choose that name.

;-)


You revealed my secret


Could easily be "mixed samples" on the other end instead of intentional leaks. You know how old lab equipment could be really useful in a live seafood market.


Lament from one camp that political discourse has been more polarized is often hard to distinguish from them hating on the world for leaving their camp. People don't have to stay in your camp forever, aka "not polarized".


Sounds like pr when Google is under antitrust investigation


Arm has said that they are not gonna work with Huawei.

https://www.bbc.com/news/technology-48363772


Isn't it's darkest secret the fact that we can't shut it down because the inmates don't want to face civilian trial in NYC and they have nowhere else to go?


This looks relevant:

« In June, 2004, the Supreme Court ruled that Guantánamo detainees could challenge the grounds for their detention. It became fashionable for high-profile corporate-law firms to represent Guantánamo clients, pro bono, but many detainees rejected representation, because they thought it was a ploy to lend legitimacy to an unjust detention. »


Where did you hear they don't want to face civilian trial and even if true where did you hear they could refuse to have a trial and also where did you hear they would be tried in new york?


I believe it is the US Gov who doesn't want them to go to trial due to lack of evidence / evidence from torture is not usable for all that has gone on to come out in a more public forum


Sorry if that sounds cynic, but maybe not all of them have full confidence in the US justice system?


well unfortunately the US justice system is the one they are going to have to deal with. you don't really get a preference in such things.


It is my understanding that almost the exact opposite of this is true.


Nah because if they did that it would give them rights.


Cambridge can't even fix potholes and plow snow, but this is where they decide to spend money. Some real galaxy brains.


Tell that to the guy that tried to create HIV resistance babies in China. He had a decent lab yet both babies he created didn't have ccr5 hit: the crispr missed target.


Who fact checks the fact checkers?


Interesting idea - are you more likely to be lied to in a) an authoritarian state with laws against fake news b) a democratic state with laws against fake news, or c) a democratic state without laws against fake news?


To be honest, you are likely to be lied to in any of those nations. And none are any more likely than the others to put forward the truth. (Or, "facts" if you prefer.)

So you can't really judge these different nations based on whether government officials lie to you. They all will, let's just put that on the table and accept it. So you need to judge them based on other things. What other freedoms do you enjoy? How many other freedoms? What is the economic upside? (Lots of freedom with no economic opportunity gets old very fast, just ask the average Kenyan.) etc etc etc.

But, yeah, access to 100% of the facts and truth is not something that most of the world's residents will ever have access to unfortunately.


What's democratic about outlawing speech?


"Democracy is a system of government where the citizens exercise power by voting." https://en.wikipedia.org/wiki/Democracy

If the citizens or elected representatives in a democracy voted to start censoring speech, but continued to empower citizens to vote, it would still be a democratic state in spite of the censorship. An illiberal one, but still democratic.


>it would still be a democratic state

Only through the first election cycle [1].

Your idea is valid in a static, nothing-ever-changes world, with no significant political dynamics to speak of. However, out in the world as we know it, political processes run all the time, the proverbial pendulum swings, and consensus is formed via vocal advocacy and protests.

Right now we have four basic things defined as "political speech": person-to-person conversations; mass communication (press, TV, radio, online videos); peaceful physical actions like assembly and manifestations; and finally donations to candidates, parties and PACs. We protect each and every recognized form of "political speech" exactly because without it the important changes could not happen.

In a world with limited communication, you'd have on one side a small ruling clique, semi detached from daily concerns, a large mass of disenfranchised and zoned out people coasting along in the middle, and on the other side you'd have a small fraction of disenfranchised and either abused or outright persecuted people that can't even raise the wider society's awareness. This is an unstable state, leading to societal collapse in one way or another.

Let people speak effectively, lest they could not protest problems or oppression. Let people speak effectively, lest the wider society couldn't even learn of the problems faced by sub-groups. Being heard is the first, necessary step to having wants and grievances addressed.

--

[1] tiptoeing around Godwin's law


>> it would still be a democratic state

> Only through the first election cycle.

I'd like to point out that the incumbent party of the Singapore government has been in power since 1959.

It has 93% of the seats in our legislature, while only having 69% of the popular vote (it was 60% in 2011, but Lee Kuan Yew's death and Singapore's 50th anniversary probably helped boost it a bit).

They have no incentive to improve on the voting system, nor do many people in the electorate care. The government gives out annual cash bonuses of approximately $300 [1] to the majority of the population, which seems to appease them a bit.

Edit: I initially said 1965, but it was actually 1959. [2]

[1] https://www.gstvoucher.gov.sg/Pages/Cash.aspx

[2] https://en.wikipedia.org/wiki/People%27s_Action_Party


To be clear, I strongly support free speech rights for many reasons, one of which is that I agree with you that they make democracy and society stronger.

But you're being reductive. Countries around the world suppress speech to varying degrees without collapsing or becoming autocracies in a single election cycle. Many European countries have notably less freedom of speech in specific areas than the US but are even still widely considered liberal democracies (praising Nazism is illegal in Germany; UK defamation laws impose some of the highest burden of proof on the defendant in the Western world).


>still widely considered liberal democracies

The Yellow Vests in France may disagree - for several weeks they were protesting in large numbers, every weekend, and yet their wants and needs haven't really registered in popular awareness. Why is that?

My point hinges on ability to raise awareness of issues, to break into public consciousness with grievances. That's different from espousing a particular political ideology. That doesn't even technically require a liberal democracy, but specifically requires having proper channels for being heard out, and conduct society-wide negotiations. The political facet of freedom of speech.

We here in Europe aren't in need of propagating authoritarian ideologies; that would not help in the least. However there's a growing need to be able to discuss and form consensus on issues of immigration, taxation, and growing worries over the retirement pension systems in the face of shrinking populations. The subjects effectively became tabu in recent years, up to the point of having developed a wide array of euphemisms. There's growing frustration over them.

Right now the subject of immigration is mostly discussed by far right and far left parties and movements. This causes people interested in the subject to drift towards extremes. It should instead be up for discussion - and negotiations - on the political mainstream. The subject by and of itself is orthogonal to political ideology. Suffices to point out that the major political factions, both in USA and in Europe, have repeatedly shifted back and forth on the subject over the recent decades.


I'm really not sure what point you're making. Are you saying:

• it was inaccurate of me to characterize the UK, Germany, and France as being liberal democracies according to the consensus definition of the term?

• the consensus definition of the term is wrong or bad, and the term should have a different definition that France, or Germany, or the UK wouldn't satisfy?

• something else entirely?

P.S. I also am not sure what it means for the Yellow Vests' wants and needs to have not "really registered". Didn't Macron rapidly rescind the gas tax that initially sparked their anger, and then make a bunch more policy concessions besides?


People tend to think "democracy" = "freedom". But a state can have a massive slave population, and still be a "democracy" as long as a group of citizens vote.


But in order to be a democracy, do you not need the ability for everyone to freely express their political positions as to win over more political allies? If one party controlled all speech then voted that the opposition no longer had any free speech...they would control the entire national conversation. Hardly democratic. North Korea labels itself a "democracy" and holds elections, but no sane person actually believes that claim. The act of voting itself is only one piece of democracy.


To be clear, I strongly support free speech rights for many reasons, one of which is that I agree with you that they make for a better democracy and better society.

But you're being reductive. Of course the act of voting itself is meaningless if state doesn't vest power in it, but countries around the world suppress speech to varying degrees yet are stable, not in any immediate danger of turning into North Korea, and vest enough legitimacy in their elections as to be widely considered democracies, if illiberal ones. Many European countries have notably less freedom of speech in specific areas than the US but are even still widely considered liberal democracies (praising Nazism is illegal in Germany; UK defamation laws impose some of the highest burden of proof on the defendant in the Western world).


Sounds like a great oppurtunity; e.g. someone could start metafactcheck.org.


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