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I work in a lab. Let me give you some ideea of what's happening:

- Some machines use embedded MCUs with no operating systems. I haven't seen one of these in the last 15 years. The last DNA extraction machine we got (a glorified sample shaker with 2 stepper motors) runs Win10! It has no keyboard, no network, and absolutely no ports of any kind (or at least not accessible without dissasembling the machine). A 8051 could do the job and still have memory left for Pong. [1]

- Very old machines run MSDOS and a proprietary software that directly talks to hardware ISA boards via I/O ports - no drivers. That software can't be ported to Windows2000+ because of the same reasons DOS games can't run in Win2000 - the kernel won't allow direct hardware access. Linux doens't allow it either.

- Newer machines run Windows 2000/XP/7/10, many of them offline. Some of them were updated to run Win10 from older versions, with the same app version (just Windows updated).

- Since Win10 can no longer be bought, newer machines run Win11 with permanent internet connection and they are minimally customized - the vendors left all ads, Copilot, Store and the kitchen sink installed. It's atrocious to work with those, but nobody cares. The management that make the decisions to buy the machines never ever touch them or even see them, and they don't take advice or feedback from us (or anyone else but accounting).

[1] https://gentechbio.com/en/producto/panamax-48/



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