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Seems like you need to increase the usage of it as your body starts adapting to it and the weight loss plateaus. IMO, I think the hype around this drug is a bit much and I expect a significant number of users won't be able to meet or maintain their weight loss goals with it.


I do think the dosing schedule should receive more personalization per-person. The schedule for tirzepatide is 2.5mg a week for the first month, then 5mg, then 7.5, etc.

For me, a month in on 2.5, I was still struggling to force myself to eat enough. Zero need to move up. Some people don't feel anything at all until they're on 7.5mg, though.

There's also a lot of people seeing better success with smaller doses more frequently, too. Instead of moving up to 5mg, I'm doing 2mg every 3-4 days. Loss is still steady and I'm not seeing any indication I'll need to bump up any time soon.




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