pg: "Being too cynical will cause you to miss out on the most important phase changes."
Defaulting to "no" might get you the right answer the majority of the time, but it also makes you miss the times that "yes" is correct. And correct things that are a radical departure from the status quo are probably the most important and useful to get right.
Skepticism is good (it's still ambiguous whether LK-99 is anything at all), but pessimistic cynicism is not the same thing.
The brain loves an excuse to apply a noise cutting heuristic. There was an article a while back about that being a problem for general physicians, where the problem is usually simple, but very very rarely something serious. A doctor can appear good when they get it right 99% of the time, but they might achieve that by defaulting to “you’re fine, here’s some (ibuprofen/antibiotic/antihistamine/etc)”. Thus, their actual job is to identify that 1% with reasonable accuracy.
Defaulting to "no" might get you the right answer the majority of the time, but it also makes you miss the times that "yes" is correct. And correct things that are a radical departure from the status quo are probably the most important and useful to get right.
Skepticism is good (it's still ambiguous whether LK-99 is anything at all), but pessimistic cynicism is not the same thing.