Unfortunately, research into this disease is hugely underfunded relative to its societal impact. Even if it is a biopsychosocial condition, which I highly doubt, its effect on millions of sufferers begs for proven solutions. One of the more promising avenues currently is the metabolic trap hypothesis:
I've suffered from CFS for 17 years, and spent 13 of those looking for a psychological solution, since all my blood tests were fine. Finally accepting the physical nature of my condition has led me to pacing my exertions so as to minimize my symptoms, which is a huge improvement. I would be completely willing to accept a psychological cure today if it actually worked. The best biopsychosocial research is the PACE trial into CBT and graded exercise therapy, which has been highly controversial in its methodology, but even taken at face value, has shown only marginal improvements, and certainly no objective end to disabling symptoms for any significant number of sufferers. (I'll let you look that one up since most sources are highly biased either pro or con.) I myself have tried both CBT and GET multiple times with no improvement in my condition.
http://www.shoutoutaboutme.com/testing/the-2-day-cpet-a-gold...
Unfortunately, research into this disease is hugely underfunded relative to its societal impact. Even if it is a biopsychosocial condition, which I highly doubt, its effect on millions of sufferers begs for proven solutions. One of the more promising avenues currently is the metabolic trap hypothesis:
https://www.healthrising.org/blog/2018/10/18/the-metabolic-t...
I've suffered from CFS for 17 years, and spent 13 of those looking for a psychological solution, since all my blood tests were fine. Finally accepting the physical nature of my condition has led me to pacing my exertions so as to minimize my symptoms, which is a huge improvement. I would be completely willing to accept a psychological cure today if it actually worked. The best biopsychosocial research is the PACE trial into CBT and graded exercise therapy, which has been highly controversial in its methodology, but even taken at face value, has shown only marginal improvements, and certainly no objective end to disabling symptoms for any significant number of sufferers. (I'll let you look that one up since most sources are highly biased either pro or con.) I myself have tried both CBT and GET multiple times with no improvement in my condition.